Robust Optimization of Dose-Volume Metrics for Prostate HDR-Brachytherapy Incorporating Target and OAR Volume Delineation Uncertainties
نویسندگان
چکیده
منابع مشابه
Robust optimization of dose-volume metrics for prostate HDR-brachytherapy incorporating target volume delineation uncertainties
In radiation therapy planning, uncertainties in target volume definition yield a risk of underdosing the tumor. The classical way to prevent this in the context of external beam radiotherapy (EBRT) has been to expand the clinical target volume (CTV) with an isotropic margin to obtain the planning target volume (PTV). However, the EBRT-based PTV concept is not directly applicable to brachytherap...
متن کاملRobust optimization of dose-volume metrics for prostate HDR-brachytherapy incorporating target- and OAR volume delineation uncertainties
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Background: For the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, MRSI was used as a molecular imaging modality with MRI and CT images. Materials and Methods: The images of 20 prostate cancer patients were used in this study. The MR and MRSI images were registered with CT ones using non-rigid registration technique. The CT based planning (BP), CT/MR...
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PURPOSE The quality of HDR-BT of prostate cancer depends on operator skills, anatomy, prostate volume and relation to surrounding tissues as well as previous diseases and treatments of a patient. There is a rare data available concerning the minimum number of needles and its influence on dose distribution, side effects and long-term outcome. The study is to determine the minimal prostate volume...
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background: for the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, mrsi was used as a molecular imaging modality with mri and ct images. materials and methods: the images of 20 prostate cancer patients were used in this study. the mr and mrsi images were registered with ct ones using non-rigid registration technique. the ct based planning (bp), ct/mr...
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ژورنال
عنوان ژورنال: INFORMS Journal on Computing
سال: 2019
ISSN: 1091-9856,1526-5528
DOI: 10.1287/ijoc.2018.0815